4853 Drug Discovery, Introduction

Although the fundamental principles of drug discovery are well established, the tools, technologies and methods used in the discovery and development of safe and effective drugs are constantly evolving. This introductory course provides a framework for understanding the complex process of drug discovery, from target selection to drug optimization. The instructor and a team of guest speakers address fundamental principles and cutting-edge approaches to drug discovery and provide strategies for implementing and integrating various scientific approaches. Topics include target selection (genomic and biopharmaceutical); validation; lead discovery, including primary and secondary screening and selectivity assays; optimization of properties, including combinatorial and medicinal chemistry, molecular modeling and biological approaches; pharmacokinetics and ADME; and toxicology.

"Molecular Biology, Introduction."

Certificate Program in Bioinformatics

Certificate Program in Biotechnology