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Knowledge of how gene expression is regulated is essential to understanding cellular structure and function, both in normal cells and in the disease state.
DNA microarrays, also known as DNA or gene chips, have revolutionized the field of molecular biology. They provide the ability to quickly and efficiently analyze complex biological processes. As a result, they play a leading role in the discovery of new biopharmaceuticals.
Next Generation DNA Sequencing (NGS) has made it possible to sequence a human genome at an incredibly low cost, vastly expanding the potential applications of genomics in cancer diagnostics, pathogen identification, forensic human identification and genetic disease diagnosis. This course begins with the basics of this revolutionary process and then delves into specific applications of NGS in research and clinical settings. The course covers the primary methods used for highly parallel sequencing.
High-throughput efforts by biopharmaceutical companies focusing on the discovery and validation of new targets and identifying agents that affect them will uncover a multitude of new chemical and biological agents that have the potential for clinical benefits. However, before such agents can be tested and used widely in patients, safety and acceptable toxicity to critical organs must be demonstrated.
This course surveys the adverse effects resulting from the interaction of chemical agents with living systems.
California is at the forefront of stem cell research and the industry continues to offer exciting opportunities in the Bay Area. This introduction to stem cells and their applications is geared towards professionals in the pharmaceutical, biotech, medical device, and healthcare industries. It addresses the basic biology and clinical applications of embryonic and adult stem cell therapies, provides a market overview of stem cell startup companies, and touches on the FDA regulation of biologic products.
Rapid advancements in molecular diagnostics are drawing the attention of the bioscience industry, regulatory agencies, clinicians, patients and insurers alike. This survey course provides a foundation in the basic science and technologies that underlie the emerging field of molecular diagnostics, and highlights potential impacts on the healthcare landscape.
Interactive lectures explore the intricate relationship between the human genome and diagnostic tests.
This course introduces the fundamental principles of human physiology in health and disease, and provides insight into emerging and established therapies used to treat a range of disease processes. Designed for individuals who lack formal medical training, the course introduces the hierarchical organization of the body, from cells to coordinated organ systems, and continues with a discussion of the key integrative/homeostatic control mechanisms.
Understanding the molecular and cellular basis of cancer is essential for the development of new therapeutic strategies and diagnostic tools. This course explores the basic biology of cancer, including the key cellular processes and players, whose alteration leads to uncontrolled cell proliferation. Topics include the pathology and genetic basis of cancer, the immune system, and the role of infectious agents and environmental carcinogens in the disease process. You'll also discuss emerging therapies and strategies for cancer prevention.
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This course explores the fundamentals of statistical methods and reasoning. Topics include descriptive methods, data gathering, probability, interval estimation, significance tests, one- and two-sample problems, categorical data analysis, correlation and regression. The instructor will demonstrate the use of spreadsheets and statistical software to analyze and interpret data. Examples are drawn from a variety of fields including biology, business and marketing. While not too mathematically rigorous for the novice, the course provides some mathematical detail to illustrate basic concepts.